Critical synopsis and key questions in brain death determination

Updates in the determination of brain death.

The concept of brain death must be accurately determined and defined, especially in the light of the latest legislation on brain blood flow measurements.

[Definition and determination of brain death].

Circulatory Arrest, Brain Arrest and Death Determination

Technological advances, particularly in the capacity to support, replace or transplant failing organs, continue to challenge and refine our understanding of human death. Given the ability to reanimate organs before and after death, both inside and outside of the body, through reinstitution of oxygenated circulation, concepts related to death of organs (e.g. cardiac death) are no longer valid. T...

Simulation-based training in brain death determination.

BACKGROUND Despite straightforward guidelines on brain death determination by the American Academy of Neurology (AAN), substantial practice variability exists internationally, between states, and among institutions. We created a simulation-based training course on proper determination based on the AAN practice parameters to address and assess knowledge and practice gaps at our institution. ME...

Vitamin D and the brain: key questions for future research.

Over the last decade a convergent body of evidence has emerged from epidemiology, animal experiments and clinical trials which links low vitamin D status with a range of adverse neuropsychiatric outcomes. This research demonstrates that the timing of exposure to low vitamin D influences the nature of brain phenotypes, as exposures during gestation versus adulthood result in different phenotypes...